The Preoperative Use of Intravenous Palonosetron to Prevent Postoperative Nausea and Vomiting Rebecca Scott Caromont Regional Medical Center - Gastonia, NC
Background/Purpose: Assess the impact of a preoperative, prophylactic antiemetic protocol utilizing palonosetron on the incidence of postoperative nausea and vomiting in patients undergoing planned surgical procedures.
Methodology: Eligible participants were American Society of Anesthesiologists Physical Class I, II, and III patients at least 18 years of age undergoing planned hysterectomies, colon resections, and total joint replacement procedures with duration of hospital stay greater than or equal to 18 hours or at least one midnight after surgery. Chart reviews of patients undergoing procedures between November 1, 2017 and February 1, 2018 were compared with chart reviews of procedures between December 1, 2018 and March 31, 2019, after the addition of palonosetron to a preoperative protocol.
Presentation Objective: Identify potential benefits for the use of palonosetron as a preoperative, prophylactic medication.
Self-Assessment: How can pharmacists decrease drug burden for patient benefit through modification of medication protocols?